Intradermal Application of Modern (cell-culture and Embryonating Egg) Rabies Vaccines for Human Rabies Post-exposure Treatment

In developing countries, where more than 99% of all human rabies deaths occur, nervous tissue antirabies vaccines are still the most widely used because of their relatively low cost and despite their variable potency and the risk of neurological complications. The supplies of modern and safe vaccines for many developing countries are grossly inadequate whereas the demand for affordable and safe human post-exposure treatment (PET) is increasing in the developing world. Although the costs of modern vaccines are decreasing, the current price of a full intramuscular vaccine treatment is far beyond what an average family in Africa or Asia can afford.